PD_Seniors_SEN008 Hormone replacement therapy can be either estrogen alone (called estrogen replacement therapy, or ERT), or estrogen and progesterone combined. This combination is referred to as hormone replacement therapy (HRT). Progesterone is usually given in the form of progestins, which are synthetic forms of the naturally occurring hormone progesterone. While once widely used, HRT now has a more limited role because of concerns about its safety.

Estrogen is most commonly given in these forms:

  • Pill or tablet
  • Vaginal cream
  • Vaginal ring insert
  • Patch
  • Skin gel

Progestin is available in these forms:

  • Pill (can be combined with estrogen)
  • Intrauterine device (IUD)
  • Vaginal capsule
  • Injection
  • Implant
  • Skin gel