Chronic renal failure occurs when a kidney is damaged and cannot work effectively. Kidneys clean waste from the blood, which passes out of the body in urine. If the disease is caught early, damage to the kidney can be slowed, but not stopped completely.

The Kidneys
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Chronic renal failure is often caused by diseases such as high blood pressure, diabetes, and various kidney diseases ( kidney stone, benign prostatic hypertrophy, polycystic kidney disease, drug-induced kidney disease). In some patients, severe infections (eg, hepatitis B or HIV) or autoimmune diseases (eg, lupus) can also cause kidney disease.